In a nine week study, Male C57BL/6 mice were subjected to either 1) unrestricted feeding (ad lib. feeding) where the mice could eat as much as they wanted or, 2) unrestricted feeding with benaGene supplementation.  After 2.5 weeks, the mice eating the benaGene supplement did not gain as much weight as the control group.  This is due to the production of beneficial proteins that block fat creation and increase fat use, which results in a lower overall weight as compared with the control group.  The weight "span" of the benaGene supplemented mice also changed--- Low weight mice gain weight, overweight mice lose weight, with an overall average lower than the control group.  This is consistent with a decrease in insulin resistance.